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Home > Ihre Nephrologie in Dresden > Offene Stellen > Predoctoral Fellow/PhD student (f/m/x)

The main focus of the Division of Nephrology of the Department of Internal Medicine III (Head: Prof. Dr. med. Ch. Hugo) is the diagnosis and treatment of renal diseases and hypertension. Nephrology is a division with a lot of research possibilities with national and international collaborations and includes a wide variety of basic and patient-related clinical research.

 

The Experimental Lab of the Division of Nephrology (Head: Prof. Dr. Dr. Vladimir Todorov) has a vacant position for

Predoctoral Fellow/PhD student (f/m/x)

 

The position is immediately available. The contract is planned for 36 months, but will start with a period of 12 months. The financing is secured for 36 months, but we initially offer a 12 months contract with optional extension upon successful integration into the research team.

The successful candidate will be incorporated into ongoing DFG- and industry-sponsored projects on the characterization of renin cell-dependent protective and regenerative mechanisms in the kidney.

Our group focuses on regenerative mechanisms in the kidney with respect to molecular and cellular interactions of resident and extrinsic cell types by generating and studying transgenic mice. By creating a triple transgenic mouse model, we have identified the renin cells as precursor niche that also protects the renal microvascular endothelium by producing pro-angiogenic and pro-fibrotic factors in a balanced way (Starke et al, 2015, doi: 10.1681/ASN.2014030265; Steglich et al. 2020, doi: 10.1007/112_2020_27; Kessel et al. 2021, doi: 10.1152/ajprenal.00151.2021).

Based on our previous works (Lachmann et al. 2017, doi: 10.1681/ASN.2017020173; Steglich et al. 2019, doi: 10.1007/s00424-019-02298-9) the PhD student will be expected to work on the characterization of a transgenic mouse model with reduced number of renin cells under conditions where homeostasis is challenged (e.g. physical stress, different salt and fat diets, etc.). Within her/his work, IHC, FACS, cell sorting, single cell transcriptome and proteome analysis, as well as cell culture assays will be the techniques to be used (all of which are established in the group). For further information please click here.

Your Profile:

  • You have or you almost finished your Master/Diploma - or equivalent degree in biology, biochemistry, biomedicine or closely related subject.
  • You are interested in microscopy techniques as well data and statistical analysis preferably using programming language R. We have a competent team that will introduce you to all techniques. 
  • You are familiar with performing assays like IHC, PCR and immunofluorescence. Preferably, you have already a FELASA B (or equivalent) certificate.
  • You are a great team worker and you can effectively communicate in English. Knowledge of German is a plus.
  • You enjoy studying fundamental questions in biology. You can work independently and diligently and enjoy innovation.

 

We offer:

  • An interesting research field with an excellent basic research scientific campus including the Center for Regenerative Therapies Dresden (CRTD), the Medical Faculty, the BIOTEC and the Max-Planck Institute for Cell Biology and Genetics in close neighbourhood to the historic city of Dresden
  • Realization of own ideas and employment in an innovative interdisciplinary team
  • Arranging for flexible working hours to find a balance between work and family life 
  • Using our internal prevention program including courses and fitness in our Carus Vital health Center 
  • Taking part in job-oriented educational courses in our Carus Akademie
  • Providing for the future in the form of a company pension plan
  • A Position according to the TV-L conditions

Application of women is appreciated. Disabled persons with equal qualification will be preferred. 

 

We kindly ask you to apply preferably via our online form to make the selection process faster and more effective. Of course, we also consider your written application without any disadvantages. We look forward to receiving your application, until December, 31st 2022 online with registration number MK30922365.

For further information, please contact Susanne Dollfus by phone 0351-458-4233 or by e-mail: susanne.dollfus@uniklinikum-dresden.de 

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